Features of stomach and duodenum peptic ulcer in patients with mesenteric atherosclerosis

Introduction . The high frequency of complicated forms the stomach and duodenum peptic ulcer (PU) in patients with atherosclerosis requires study additional factors ulcerogenesis addition to infection Helicobacter pylori ( H. pylor i) use non-steroidal anti-inflammatory drugs (NSAIDs). Currently, there is no clear understanding role mesenteric artery (MA) development gastroduodenal ulcers. purpose To evaluate contribution MA gastric duodenal multifocal atherosclerosis. Material methods included 91 two or more vascular beds period from 2019 2021. examination determination gastrin-17, pepsinogen I, II antibodies IgG concentration blood serum, as well multispiral computed tomoangiography abdominal aortic branches esophagogastroduodenoscopy histological examination. Results were divided into groups: group I – 36 (39.6%) PU, 55 (60.4%) without PU. A frequent occurrence hemodynamically significant stenosis a higher percentage superior (SMA) noted. positive correlation was found between severity erosive ulcerative lesions SMA stenosis, levels II. combination PU characterized by lesser pain syndrome (p = 0.049). Risk for identified: (OR 4.953; CI 1.571–15.608); than 8 points on HADS depression scale 2.970; 1.062–8.320) Audit questionnaire 5.787; 1.348–24.837). Conclusions atherosclerosis, subclinical depression, health-threatening alcohol consumption. asymptomatic course.